Senda is harnessing millions of years of evolution to pioneer fully programmable medicines.
Realizing the full potential of the information molecule era
Following a lengthy period of drug development driven more by trial and error than precision targeting, recent advances in our understanding of the genetic code—a natural programming language—have ushered in the age of rationally designed information molecules.
We can now program various information molecules —mRNA, DNA, siRNA, gene editors, and more—but have yet to fully deliver on the enormous potential of programmable medicines. There is a critical missing link: the ability to get these information molecules to cells of interest in the body.
Programming to the cell using the code from natural nanoparticles
Senda is founded on the insight that human and non-human cells coevolved to exchange molecules continually. Natural nanoparticles evolved to shuttle information biomolecules into human cells, displaying tropism, potency, and repeatability in their interactions.
Senda is the first company to decode this natural programming language to unlock full programming to the cell.
More diverse targeting options than existing methods
There is an expansive multitude of natural nanoparticles carrying unique chemical addresses. Senda is deconstructing these addresses and mapping them in a vast proprietary catalog derived from natural nanoparticles extracted from species across 4 kingdoms of life.
Harnessing nature’s complete code to make more effective therapeutics
Senda deconstructs the components of these particles into a chemical code that forms the basis of our nanoparticle programming language.
Using the subcomponents, we are programming a wide range of therapeutically desirable bioproperties, such as cell tropism and repeatable dosing, via previously inaccessible routes of administration.